LEVELSET BIO

Building Pharma-Ready Assets with Disciplined Execution

LevelSet Bio is an integrated drug development company designed to turn high-potential science into de-risked, pharma-ready programs through repeatable, portfolio-scale execution.

Milestone-Driven Capital

De-Risked Development

Pharma-Ready Programs

WHO WE ARE

WHO WE ARE

LevelSet Bio was founded to address one of the biggest failure points in biotech... execution

Too many promising drug programs stall or fail for reasons that have little to do with biology and everything to do with fragmented development, misaligned capital and reactive decision-making.

Our mission is to build a capital-efficient drug development platform that systematically advances high-potential assets with institutional-grade execution. We design programs to withstand regulatory, operational and capital constraints from day one, so strong science is translated into credible, pharma-ready programs.

VISION

We aim to set a new standard for repeatable value creation in drug development, where science, capital and R&D execution are successfully centralized.

We aim to set a new standard for repeatable value creation in drug development, where science, capital and R&D execution are successfully centralized.

We aim to set a new standard for repeatable value creation in drug development, where science, capital and R&D execution are successfully centralized.

What our Approach Enables

Builds a scalable clinical-stage portfolio combining AI insights, disciplined execution and capital efficiency to consistently develop pharma-ready assets.

Portfolio Engine

Centralized portfolio-scale R&D engine

Pharma Alignment

Development design with pharma buyers in mind

Capital Efficiency

Capital-efficient milestone gating

Unified Execution

Integrated CMC, regulatory and clinical execution

Risk Discipline

Structural risk management and early kill criteria

Clean Data Packages

Clean, diligence-ready data packages for partnering

TEAM

Our People Dedicated to Scaling your Assets

Experienced investors and operators across drug development, IP strategy, investing in and scaling companies, asset transactions, supported by global network of advisors.

Leadership Team

Ami Patel Shah, JD

Managing Partner

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Marta New, PhD, MBA

Founding Partner

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Advisory Board

Alexandre LeBeaut, MD

Scientific Advisor

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Matt Tremblay, PhD

Scientific Advisor

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Dennis Liotta, PhD

Scientific Advisor

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Jeni Fan

Industry Advisor

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Partners

LevelSet Bio partners with best-in-class organizations across AI, translational science and global clinical development to build a repeatable, capital-efficient drug development engine.

This ecosystem enables faster decision-making, smarter biomarker strategy and scalable portfolio execution.

Pipeline

Have an asset that fits our model?

LevelSet Bio is actively growing its initial portfolio through in-licensing late preclincal to early clinical assets, advancing high-potential programs through disciplined development to value-creating inflection points.

Immunology & Inflammation

Novel immunomodulatory approaches with biomarker-driven strategies targeting chronic inflammatory diseases, including IBD and autoimmune disorders

Oncology

Precision oncology assets with strong biological rationale, biomarker-defined populations, and clear differentiation in solid and hematologic tumors

Neurodegenerative

Programs addressing high-unmet-need neurological diseases, incorporating translational biomarkers to enable patient stratification and development decisions

Metabolic/ Obesity

Next-generation metabolic therapies with emerging biomarker strategies to improve patient selection, efficacy, and long-term outcomes

Underserved Disease Areas

High-impact programs in rare and underserved diseases with defined biomarkers and clear paths to differentiation and accelerated development

Immunology & Inflammation

Novel immunomodulatory approaches with biomarker-driven strategies targeting chronic inflammatory diseases, including IBD and autoimmune disorders

Oncology

Precision oncology assets with strong biological rationale, biomarker-defined populations, and clear differentiation in solid and hematologic tumors

Neurodegenerative

Programs addressing high-unmet-need neurological diseases, incorporating translational biomarkers to enable patient stratification and development decisions

Metabolic/ Obesity

Next-generation metabolic therapies with emerging biomarker strategies to improve patient selection, efficacy, and long-term outcomes

Underserved Disease Areas

High-impact programs in rare and underserved diseases with defined biomarkers and clear paths to differentiation and accelerated development

Have an asset that fits our model?

LevelSet Bio is actively growing its initial portfolio through in-licensing late preclincal to early clinical assets, advancing high-potential programs through disciplined development to value-creating inflection points.

Pipeline

Immunology & Inflammation

Novel immunomodulatory approaches with biomarker-driven strategies targeting chronic inflammatory diseases, including IBD and autoimmune disorders

Oncology

Precision oncology assets with strong biological rationale, biomarker-defined populations, and clear differentiation in solid and hematologic tumors

Neurodegenerative

Programs addressing high-unmet-need neurological diseases, incorporating translational biomarkers to enable patient stratification and development decisions

Metabolic/ Obesity

Next-generation metabolic therapies with emerging biomarker strategies to improve patient selection, efficacy, and long-term outcomes

Underserved Disease Areas

High-impact programs in rare and underserved diseases with defined biomarkers and clear paths to differentiation and accelerated development

Have an asset that fits our model?

LevelSet Bio is actively growing its initial portfolio through in-licensing late preclincal to early clinical assets, advancing high-potential programs through disciplined development to value-creating inflection points.

Pipeline

Interested in partnering or out-licensing your drug assets?

We are actively acquiring advanced preclinical-stage and early clinical assets across modalities, with strong translational rationale, clear differentiation and well-defined development paths.

Address

Biotech+ Hub at Pegasus Park3000 Pegasus Park DriveDallas, TX 75247, US

Contact

info@levelset.bio

Interested in partnering or out-licensing your drug assets?

We are actively acquiring advanced preclinical-stage and early clinical assets across modalities, with strong translational rationale, clear differentiation and well-defined development paths.

Address

Biotech+ Hub at Pegasus Park3000 Pegasus Park DriveDallas, TX 75247, US

Contact

info@levelset.bio

Interested in partnering or out-licensing your drug assets?

We are actively acquiring advanced preclinical-stage and early clinical assets across modalities, with strong translational rationale, clear differentiation and well-defined development paths.

Address

Biotech+ Hub at Pegasus Park3000 Pegasus Park DriveDallas, TX 75247, US

Contact

info@levelset.bio